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Expression Systems

Publications, Books & Reports

Biopharmaceutical Expression Systems

New expression systems and recent improvements available for current systems have the potential to revolutionize the biopharmaceutical industry. Lower costs and efficiencies of newer expression systems are driving these changes.

This book provides you with the information you need to make the shift to increased productivity. As reflected by currently marketed products, since the advent of genetic engineering in the 1970s, there has been little basic change in the technologies used for commercial-scale manufacture of biopharmaceutical products.

Nearly all current products are manufactured using much the same old, familiar technologies – primarily using Esherichia coli (E. coli bacterium), Chinese hamster ovary (CHO) cells, and the yeast saccharomyces cerevisiae (S. cerevisiae) as hosts – technologies invented in the 1970s and commercialized in the 1980s.

>> Read more about this book

By Ronald A. Rader
Published by the BioPlan Associates, Inc.
November 2008

Also available to download as a Global Digital License

 

Download Complete Table of Contents 955k PDF

Table of Contents:

  • Broad/Platform Technologies
  • More Technologies
  • Indexes

Broad/Platform Technologies

  1. Cell-free systems
  2. Broad, cross- or multi-platform technologies
  3. Prokayotes
  4. Bacteria
  5. Yeasts
  6. Plants
  7. Eukaryotes
  8. Protozoa
  9. Animals, misc.
  10. Mammalian
  11. Chinese hamster ovary (CHO) cells
  12. Hybridomas
  13. Chickens/Poultry
  14. Human
  15. Insects

More Specific and Component Technologies

  1. Bacteria/Prokaryotes
  2. Yeasts
  3. Mammals
  4. Chinese hamster ovary (CHO) cells
  5. HEK-293 cells
  6. Plants
  7. Insects
  1. Company/Organization Index
  2. Subject Index
  3. Primary Host/Organism Index
About the Author, Ronald A. Rader

Mr. Ronald A. Rader has a B.S. (Microbiology), an M.L.S. (Library Science), and over 25 years experience as a biotechnology and pharmaceutical information specialist, author and publisher. He is a world-class expert in biotechnology and pharmaceutical information, particularly competitive intelligence, technology and market assessments, and information resources development. Mr. Rader is the author of BIOPHARMA: Biopharmaceutical Products in the U.S. and European Markets, reference concerning biopharmaceuticals. He was also author of the Antiviral Agents Bulletin, the only periodical specializing in antiviral/HIV drug and vaccine development. He also published the Federal Bio-Technology Transfer Directory, abstracting all federal, e.g., NIH, inventions and technology transfers in biotech/biomedical areas, further marketed as an online database until 2000. Recent periodical articles include:

  • “(Re)defining Biopharmaceutical” Nature Biotechnology, July 2008, 26(7), p. 743-751.
  • “Expression Systems for Process and Product Development: A Perspective on Opportunities for Innovator and Follow-on Product Developers,”BioProcess International, vol. 6, issue 6, suppl. 4, Success Stories in Protein Expression (lead article), p. 4-9, June 2008.
  • “Biopharmaceuticals: Lack of Information Disclosure Confounds Public Trust, Particularly in the Context of Biosimilars,” BioWorld Perspectives, vol. 2, issue 18, May 1, 2008.
  • “Paucity of Biopharma Approvals Raises Alarm: Lower Numbers, Novelty and Economic Impact Indicate Problems,” Genetic Engineering & Biotechnology News (GEN), March 15, 2008
  • “How Big is the World Market for Biopharmaceuticals? It All Depends How You Define Biopharmaceutical,” in Friedman, Y., Best Practices in Biotechnology Business Development, Logo Press, p. 175-85, 2008.
  • “What Is a Generic Biopharmaceutical? Biogeneric? Follow-On Protein? Biosimilar? Follow-On Biologic?” Part 1: Introduction and Basic Paradigms –BioProcess International, March 2007.
  • “What Is a Generic Biopharmaceutical? Biogeneric? Follow-On Protein? Biosimilar? Follow-On Biologic?” Part 2: Information, Nomenclature, Perceptions, and the Market – BioProcess International, May 2007.
  • Biopharmaceutical Approvals Review – Genetic Engineering News, Aug. 1, 2006
  • What is a Biopharmaceutical, Part 1: (Bio)Technology-Based Definitions –BioExecutive, March 2005.
  • What is a Biopharmaceutical, Part 2: Company and Industry Definitions –BioExecutive, May 2005.

Our Team in the News

Donnie E. Gillespie, Director, Research Projects

Donnie Gillespie has over 15 years of experience in marketing and healthcare research. She currently manages and oversees the Biotechnology Industry Council (BIC), a network of global industry experts and leaders in specialized areas of expertise within the biopharmaceutical and pharmaceutical industry. She also oversees the production and editing of industry reports and newsletters. Donnie’s […]

Leo Cai Yang, Project Manager

Leo Cai Yang, Project Manager, has sales and marketing experience in the biotech and pharma segments, including nearly 10 years in marketing and market research. He has worked with several western equipment manufacturers in the pharmaceutical and medical device industries. He is familiar with how western and Chinese business work together and can navigate the […]

Advances in Biopharmaceutical Technology in China, 2nd ed.

International Biopharma Spotlight   Society for Industrial Microbiology and Biotechnology and… LEARN MORE

News and Announcements

China Biopharma Distributors

NEW! Directory: Top 60 Distributors of Bioprocessing Supplies in China: Opportunities for Global Biopharma Suppliers to Find and Manage Local Distributors in China   Comprehensive China Biopharmaceutical Equipment and Suppliers Distributors Directory 2020 provides detailed profiles of China’s Equipment and Supply Distributors industry. Competitive landscape in China’s bioprocess equipment and consumables segment, with comprehensive information on […]

China CMO

NEW! Growth of Biopharmaceutical Contract Manufacturing Organizations in China: An In-depth Study of Emerging Opportunities Comprehensive In-depth Study provides detailed analysis of the CMO industry, its recent development and trends. Profiles of China’s Contract Manufacturing Organizations (CMOs) and Contract Development Manufacturing Organizations (CDMOs), including their capacity, history, products, scale, management, business focus, products, R&D, business and […]

Advances in Biopharmaceutical Technology in India

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Our Team in the News

Directory of Top 60 Biopharmaceutical Manufacturers in China

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China Biopharma Distributors

NEW! Directory: Top 60 Distributors of Bioprocessing Supplies in China: Opportunities for Global Biopharma Suppliers to Find and Manage Local Distributors in China   Comprehensive China Biopharmaceutical Equipment and Suppliers Distributors Directory 2020 provides detailed profiles of China’s Equipment and Supply Distributors industry. Competitive landscape in China’s bioprocess equipment and consumables segment, with comprehensive information on […]

China Biopharma Distributors

NEW! Directory: Top 60 Distributors of Bioprocessing Supplies in China: Opportunities for Global … LEARN MORE

China CMO

NEW! Growth of Biopharmaceutical Contract Manufacturing Organizations in China: An In-depth Study of … LEARN MORE

Advances in Biopharmaceutical Technology in India

International Biopharma Spotlight Advances in Biopharmaceutical Technology in India A Society for … LEARN MORE

Advances in Biopharmaceutical Technology in China, 2nd ed.

International Biopharma Spotlight   Society for Industrial Microbiology and Biotechnology and … LEARN MORE

China Biopharma Distributors

NEW! Directory: Top 60 Distributors of Bioprocessing Supplies in China: Opportunities for Global Biopharma … LEARN MORE

Directory of Top 60 Biopharmaceutical Manufacturers in China

BioPlan’s Directory of Top 60 Biopharmaceutical Manufacturers in China Completely updated, comprehensive Top 60 D … LEARN MORE

Advances in Biopharmaceutical Technology in India

International Biopharma Spotlight Advances in Biopharmaceutical Technology in India A Society for Industrial … LEARN MORE

China CMO

NEW! Growth of Biopharmaceutical Contract Manufacturing Organizations in China: An In-depth Study of Emerging … LEARN MORE

Advances in Biopharmaceutical Technology in China, 2nd ed.

International Biopharma Spotlight   Society for Industrial Microbiology and Biotechnology and BioPlan … LEARN MORE

A Quick Guide to Clinical Trials

  A Quick Guide to Clinical Trials,  2nd Ed. -  This book provides a unique view of the clinical … LEARN MORE

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