Single Use Systems: Trends and Analysis from the 21st Annual Report, 2006-2024

Key Topics

• Single-use systems
• Biopharmaceutical manufacturing
• Cost-reduction
• Industry trends
• Sustainability concerns

Source: The Annual Report and Survey on Biopharmaceutical Report presents survey data analyzing the widespread adoption of single-use systems (SUS) in biopharmaceutical manufacturing over nearly two decades.

Key themes include the economic advantages of SUS, particularly for smaller companies and clinical trials, compared to traditional stainless steel systems, despite initial concerns about leachables and extractables, scalability, and waste disposal.

The report presents survey data showing high and increasing usage rates of various SUS components across different manufacturing stages (R&D through commercial production) in various geographical locations, with China showing particularly high adoption, especially for upstream processes.

While mature SUS technologies are approaching saturation, our survey shows newer technologies like membrane adsorbers show significant growth potential.

Finally, our report examines vendor satisfaction, revealing high satisfaction with product quality but persistent concerns about cost and timely delivery.