Advances in Biopharmaceutical Technology in China
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Chapter 23:   Biotechnology and Analytical Methods in the Modernization of Traditional Chinese Herbal Medicine

Professor Zhao WANG, M.D./Ph.D.
School of Medicine
Tsinghua University
Qinghuayuan, Beijing, 100084, China
Tel/Fax: 86 10 62772240

About the Author:
Professor Zhao WANG, M.D./Ph.D. is professor of the School of Medicine, Tsinghua University, in Beijing. Dr Wang received his Doctor of Pharmaceutical Science (1996, Japan), Master of Pharmaceutics (1993, Japan), and Master of Medicine (1987, China). His research includes Molecular & Cellular Pharmacology and Toxicology of Natural Products, signal transduction, cell cycle and apoptosis; Antitumor Activity of Silymarin; Molecular Toxicological Mechanisms of Aconitum Alkaloids; Biomineralization and osteoporosis drug design targeting biomineralization-related genes. He works with anti-aging mechanisms by natural small-molecular products; Functional research on the spermatogenesis-related gene SPATA4; drug discovery for neurodegenerative diseases from traditional herbal medicines; and R&D of traditional Chinese medicine for clinical drugs and functional food. He has worked with the Dept of Pharmacology, National Okayama University Medical School (Okayama, Japan), and the Dept of Biological Sciences and Biotechnology, Tsinghua University (Beijing, China), and the School of Medicine, Tsinghua University (Beijing, China) (Professor). He is a Senior Member of the Chinese Pharmaceutical Association, the Pharmaceutical Society of Japan, the Chinese Pharmacological Society, and is on the Editorial Board of PHARMAZIE (Germany).

Traditional Chinese Medicine (TCM) has been used in China for thousands of years. It can be a great treasury of biomedical resources not only for China but also for the world. Today, the process of modernization of TCM, especially the use of herbal medicine (TCHM), is being accelerated with the application of biotechnologies such as electrophoresis, RAPD, chromatogram, and genetic, cellular, enzyme, and fermentation technologies. Recently, high throughput and high content drug screening systems are being used to expand the scope of new drug discovery in TCHM. Maintaining its traditional features, TCHM is being pushed forward by modern science in ways that will benefit healthcare around the world.

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